AN UNBIASED VIEW OF MUSCULAR DYSTROPHY TREATMENT

Recently, the antibiotic gentamicin has been tested in boys with DMD, about 10% of whom have inherited a dystrophin gene having a premature quit codon that halts the synthesis on the protein N-terminal for the dystroglycan binding area. Gentamicin suppresses chain termination, making it possible for some whole-duration dystrophin to become generate